Objective: To explore the influences of WeChat education on intestinal preparation effect in elderly patients undergoing enteroscopy. Methods: A total of 135 elderly patients who underwent enteroscopy in First Affiliated Hospital of Nanjing Medical University from February 2019 to May 2019 were enrolled. The patients were divided into group A, B and C by random number table method, 45 cases in each group. One day before the examination, group C was given traditional paper education, group B was given WeChat group health education, and group A was given traditional paper education and WeChat group health education. Th e intestinal preparation effect, compliance, occurrence of adverse reaction and nursing satisfaction were compared among the 3 groups. Results: Th e score of Boston Bowel Preparation Scale(BBPS) in group A and B was higher than that in group C. Th e adequate ratio of intestinal preparation in group A and B was higher than that in group C(82.22%, 77.78% vs 57.78%, P<0.05). One day before the examination, compliance with intestinal preparation key points such as eating semi-liquid diet, checking intraday fasting, correct usage method and usage time of intestinal cleansing agent, drinking offintestinal cleansing agent in prescribed time, and interval from taking intestinal cleansing agent for the last time to examination time within specified range in group A and B was bett er than that in group C(P<0.05).Th e incidence rates of intestinal preparation nausea and vomiting in group A and B were lower than those in group C(24.44%, 26.67% vs 46.67%. 6.67%, 6.67% vs 22.22%, P<0.05). Th e scores of satisfaction with service att itude, medication guidance, diet guidance, health education and question-answer in group A and B were higher than those in group C(P<0.05). Conclusion: WeChat group health education before 1 d of preparation is beneficial to improve intestinal preparation effect of elderly patients undergoing enteroscopy, strengthen patients compliance, reduce incidence of adverse reactions, and improve nursing satisfaction.