ObjectiveTo evaluate the treatment efficency and side effects of interventional chemotherapy with three-dimenitonal conformal radiotherapy(3DCRT)for the treatment of huge liver cancer.Methods65 patients with huge liver cancer were treated with interventional therapy and 3DCRT.ResultsThe effective rate(CR+PR) was 76.9%,and the survival rate of 1,2,3 years were 82.2%,54.5%,30.3%.The main side effects and major toxicity of radiotherapy and chemotherapy were tolerated.ConclusionsIntervenitonal therapy with three-dimentional conformal radiotherapy can significantly raise the effective rate and survival rate.