Objective In order to solve the medical hidden trouble and improve the work efficiency in the infusion process, this study designed an intelligent infusion system.Methods The intelligent infusion system consists of four parts: server, ward monitoring terminal, bedside terminal and infusion terminal. Its effectiveness and safety were verified through clinical trials in three hospitals.Results There was no significant difference between the experimental group and the control group in the overall effective rate, the main efficacy indicators such as drip rate adjustment, infusion control and alarm function, and the secondary efficacy indicators such as appearance, display function and communication distance. Only in terms of structure, the products of the experimental group involved in this study were superior to those of the control group, and the difference is statistically significant.Conclusion The intelligent infusion system designed in this study realizes the automatic and intelligent management of the whole infusion process, provides a powerful tool for the quality control of clinical work, improves the work efficiency of nursing diagnosis and treatment, and improves the patient's medical experience.