Objective To analyze the incidence and mortality of oral and throat cancer (except for nasopharyngeal cancer) in Baoshan from 2014 to 2018.Methods The standardized incidence and mortality data of oral and throat cancer (excluding nasopharyngeal cancer) from 2014 to 2018 were selected from Baoshan Cancer Registry, and the age standardized incidence rate (ASIR), age standardized mortality rate (ASMR) and estimated annual percentage change (EAPC) were calculated to describe the prevalence and trend of oral and throat cancer (excluding nasopharyngeal cancer) in Baoshan.Results From 2014 to 2018, 243 new cases of oral and throat cancer (excluding nasopharyngeal cancer) were collected in Baoshan tumor registration area, and 128 cases of oral cancer died. The crude incidence rate was 1.96/100000 to 2.99/100000, APC=10.50%. China's population standardization rate (hereinafter referred to as bid winning rate) is 1.66/100000 to 2.30/100000, APC=8.34%. The standardized rate of the world population (hereinafter referred to as the world standard rate) is 1.61/100000 to 2.17/100000, and the APC is 8.10%, showing an overall upward trend (t=3.98, 5.56, 5.51, P<0.05). From 2014 to 2018, the crude mortality rate of oral cavity and throat cancer (except nasopharyngeal cancer) in Baoshan City was 0.70 to 1.72 per 100000, APC=22.59%, the bid winning rate was 0.47 to 1.31 per 100000, APC=24.30%, the world standard rate was 0.53 to 1.27 per 100000, and APC=21.66%. The overall change trend was not statistically significant (t=2.94, 2.54, 2.59, P>0.05).Conclusion From 2014 to 2018, the incidence of oral cancer and throat cancer (except for nasopharyngeal cancer) in Baoshan City showed an upward trend. Especially for men, corresponding health education should be carried out for men to change their living habits in order to prevent the occurrence of diseases.